Gleam vs Isomorphic Labs

Side-by-side comparison of features, pricing, and ratings

Analysis reviewed Live tool data as of 2026-10-09
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At a glance

DimensionGleamIsomorphic Labs
PricingContact for pricingContact for pricing
Target CustomerClinical research sites & coordinatorsLarge pharma & research institutions
Core TechnologyBrowser extension for automated EDC data entryAI predictive & generative models for drug design
Key IntegrationsBrowser-based sources & EDCs (no custom setup)Pharma partnerships (Novartis, Johnson & Johnson)
DeploymentBrowser extension, cloud-basedCustom collaborations, no public API
Gleam
Gleam

Gleam is a browser-based AI data-entry assistant that moves source data from eSource into EDC case report forms for clinical research sites.

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Isomorphic Labs
Isomorphic Labs

Isomorphic Labs applies generative AI drug discovery to design novel molecules and predict how candidates will perform.

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Pricing
Contact Sales
Contact Sales
Plans
Contact sales
—
Popularity
3 views
7.5k views
Skill Level
Intermediate
Advanced
API Available
Platforms
Web
—
Categories
🧾 Healthcare Revenue Cycle🏥 Healthcare
🧬 Drug Discovery & Life Sciences
Features
Chrome browser extension for EDC data entry
Works alongside existing eSource and EDC with zero integrations
Three-step Fetch, Fill, Trace workflow
Quick learn: learns the structure of each CRF page in the EDC
Queue multiple CRFs to learn in parallel
Deep learn: clicks through interactive form elements to understand a CRF
Fast Fill of the current CRF with applicable source data
Tracks protocol amendments and relearns affected CRF pages
Fetch visit data from browser-based eSource in a few clicks
Simultaneous fetch of multiple sources with notification for next step
Review and approval workflow for low-confidence data
Source-build gap detection, including missing data fields
Pre-fills logs such as concomitant medications for row-by-row confirmation
View Source jumps to and scrolls to the specified eSource data
View Destination scrolls to the relevant CRF field
Drug Design Engine spanning generative molecule design through lead optimization
Predictive AI models that anticipate how candidate drugs will perform
Generative models for designing novel molecules
Builds on and beyond the Nobel-winning AlphaFold system
End-to-end research collaborations from target identification to lead optimization
Digital biology approach aimed at discovery at digital speed
Named pharma partners include Johnson & Johnson, Novartis and Eli Lilly
Joined the Virtual Biology Initiative to build foundational data for AI disease models
Funder of Biohub's $1.8B initiative to train AI models that predict cell behavior
Bioresilience framework for biological threats and health emergencies
Series B investment round announced May 2026 to scale the Drug Design Engine
Follows a $600M external raise in March 2025
President Max Jaderberg appointed November 2025 to integrate AI and science
Interdisciplinary team of drug discovery experts and ML specialists
Founded by Demis Hassabis, who serves as CEO

Who should pick which

  • Clinical Research Coordinator
    Pick: Gleam

    Gleam automates data entry into EDCs, reducing transcription errors and freeing time for patient care. It integrates with browser-based sources without sponsor approval.

  • Site Director
    Pick: Gleam

    Gleam offers sponsor-independent workflow automation, cutting data entry time and audit prep overhead, ideal for sites using multiple EDCs.

  • Pharma VP of Drug Discovery
    Pick: Isomorphic Labs

    Isomorphic Labs provides AI-first predictive and generative models for novel molecule design, with proven pharma collaborations and deep AlphaFold expertise.

  • Research Institution Seeking AI Drug Design Partner
    Pick: Isomorphic Labs

    Isomorphic Labs combines world-class AI (AlphaFold) with drug discovery experience, suitable for large-scale programs requiring rapid lead optimization.

Frequently Asked Questions

Which tool is cheaper?

Both are contact-based pricing; Gleam likely costs less for individual sites, while Isomorphic Labs involves multi-million dollar partnerships.

Can I use Isomorphic Labs directly as a software tool?

No. Isomorphic Labs operates through pharma collaborations only, not as a product or API. It's a partner for drug discovery programs.

Does Gleam require integration with my EDC?

No. Gleam works as a browser extension with any browser-based EDC, without custom integrations or sponsor approval.

Can Gleam handle paper sources?

Paper/PDF support is on the waitlist, coming soon. Currently, it works best with electronic sources.

What is the latest news about Isomorphic Labs?

Most recent: Series B in February 2026 (announced May 2026), and a collaboration with Johnson & Johnson announced January 2026.

What is the latest news about Gleam?

Recent news unrelated to product: a DNS server in Gleam, and a report on AI human labor. No product updates announced.

Are these tools competitors?

No. Gleam is for clinical data entry at sites; Isomorphic Labs is for AI drug discovery at pharma. They serve completely different markets.

Which has stronger AI?

Isomorphic Labs uses Nobel Prize-winning AlphaFold for predictive protein-ligand models. Gleam uses context-aware AI for data entry, not comparable.

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Last reviewed: July 3, 2026