SmartGym vs Isomorphic Labs

Side-by-side comparison of features, pricing, and ratings

Analysis reviewed Live tool data as of 2026-10-18
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At a glance

DimensionSmartGymIsomorphic Labs
Target AudienceApple device users (strength training)Pharma companies (drug discovery)
AI Use CasePersonalized workout plans, periodization, exercise swappingProtein-ligand prediction, novel molecule design
PlatformiOS / iPadOS / watchOS / macOSN/A (research collaborations)
Key IntegrationStrava (added in v7.8)Partnerships with Novartis & Johnson & Johnson
SmartGym
SmartGym

AI workout coach that rewrites your Apple Watch training after every session.

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Isomorphic Labs
Isomorphic Labs

Isomorphic Labs uses AI drug discovery models to design novel molecules and predict how candidate drugs will perform.

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Pricing
Freemium
Contact Sales
Plans
$0
$9.99/mo or $59.99/yr
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Popularity
4 views
7.5k views
Skill Level
Beginner-friendly
Advanced
API Available
Platforms
Mobile
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Categories
🏋️ Fitness & Nutrition
🧬 Drug Discovery & Life Sciences
Features
AI Smart Trainer adjusts weights, reps, and exercises after every logged session
Automatic whole-program rewrite at plateaus, mesocycle boundaries, and goal shifts
Periodization built on the NSCA and ACSM frameworks plus DeLorme progressive overload
730+ animated exercises with step-by-step written instructions
130+ professionally designed ready-to-run workout routines
Custom routine builder with manual exercise, set, rep, and weight setup
Custom exercises with your own uploaded images
Standalone Apple Watch app — no iPhone and no internet connection required
Inline Logging and custom keyboard for fast set entry on iPhone (v7.11, July 2026)
Redesigned Workout Summary and Routine Progress screens (v7.10, April 2026)
Custom heart rate zones with real-time display
Training load tracking and post-session effort rating (v7.9, March 2026)
Stretch suggestions, routine segments, and draft routines (v7.9, March 2026)
Strava sync and third-party workout tracking (v7.8, February 2026)
Progress charts for volume lifted, personal records, calories, and muscle-group breakdowns
Drug Design Engine spanning generative molecule design through lead optimization
Predictive AI models that anticipate how candidate drugs will perform
Generative models for designing novel molecules
Built on and beyond the Nobel-winning AlphaFold system
End-to-end research collaborations from target identification to lead optimization
Digital biology approach aimed at discovery at digital speed
Named pharma partners include Johnson & Johnson, Novartis and Eli Lilly
Joined the Virtual Biology Initiative to build foundational data for AI disease models
Funder of Biohub's $1.8B initiative to train AI models that predict cell behavior
Bioresilience framework for biological threats and health emergencies
Announced a new path to making medicines with AI
Series B announced May 2026 to scale the Drug Design Engine
Follows a $600M external raise in March 2025
President Max Jaderberg appointed November 2025 to integrate AI and science
Founded by Demis Hassabis, who serves as CEO
Integrations
Strava
Apple Health
Apple Watch

What real users say: SmartGym vs Isomorphic Labs

Not marketing copy and not our opinion — a structured sweep of public discussion (reviews, forums, communities and video comments), showing what people praise and what they complain about for each tool.

SmartGym

56 mentions across 3 sources · 100% positive (averaged across 3 sources)

Product Hunt, App Store, Bluesky

What users praise

  • • Excellent Apple Watch integration with full offline independence
  • • AI Smart Trainer uses periodization to auto-adjust weights and reps
  • • Over 730 animated exercises with step-by-step instructions
  • • 130+ professionally designed, ready-to-use workouts

What frustrates them

  • • Only available on Apple devices, no Android or web
  • • Mac subscription popup lacks close button in reported bug
  • • Full features require a subscription after 7-day trial
  • • Limited negative feedback sample may hide real issues

Researched Jul 3, 2026

Isomorphic Labs

No verifiable community signal. We scanned public discussion on Oct 14, 2026 and found posts matching the name “Isomorphic Labs”, but could not establish that they are about this product rather than something else sharing its name. Rather than publish a score built on the wrong subject, we publish none.

Who should pick which

  • Apple Watch fitness enthusiast
    Pick: SmartGym

    SmartGym is the only app here, designed for Apple devices with offline watch support, 730+ exercises, and AI periodization. Perfect for tracking strength training progress.

  • Big pharma VP of R&D
    Pick: Isomorphic Labs

    Isomorphic Labs partners with Novartis and J&J for large‑scale AI drug discovery. Their Drug Design Engine leverages AlphaFold for predictive protein‑ligand modeling—ideal for accelerated lead optimization.

  • Athlete wanting customizable AI coaching
    Pick: SmartGym

    SmartGym’s Smart Trainer adjusts weights and reps based on actual performance. Latest update adds custom exercises and heart‑rate zones for fine‑tuned training.

  • Early‑stage biotech startup
    Pick: Isomorphic Labs

    If you seek a deep‑pocketed pharma partner with foundational AI (AlphaFold), Isomorphic Labs is the only option. Their collaboration model is built for long‑term drug development programs.

Frequently Asked Questions

Can I use SmartGym on Android?

No. SmartGym is exclusive to Apple devices: iPhone, iPad, Mac, and Apple Watch.

Does Isomorphic Labs offer a public API?

No. Isomorphic Labs works only through direct pharma partnerships with Novartis and Johnson & Johnson.

What does the SmartGym subscription cost?

SmartGym Premium costs $9.99/month or $49.99/year. A free tier exists with limited features.

How much does Isomorphic Labs charge?

Pricing is not public; it is negotiated per partnership, likely involving multi‑million dollar commitments.

Does SmartGym integrate with Strava?

Yes, Strava sync was added in SmartGym v7.8 (Feb 2026).

What is the latest news about Isomorphic Labs?

Isomorphic Labs closed a Series B in February 2026, after a $600M external investment round in 2025. It also established US operations and appointed a CMO.

Can I create custom workouts in SmartGym?

Yes. You can create routines from scratch or paste text using Apple Intelligence. The latest v7.10 also adds custom exercises to the Smart Trainer.

Is SmartGym good for beginners?

Yes, it includes 730+ animated exercises with step‑by‑step instructions and automatic progression via the Smart Trainer.

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Last reviewed: July 3, 2026