SmartGym vs Isomorphic Labs
Side-by-side comparison of features, pricing, and ratings
At a glance
| Dimension | SmartGym | Isomorphic Labs |
|---|---|---|
| Target Audience | Apple device users (strength training) | Pharma companies (drug discovery) |
| AI Use Case | Personalized workout plans, periodization, exercise swapping | Protein-ligand prediction, novel molecule design |
| Platform | iOS / iPadOS / watchOS / macOS | N/A (research collaborations) |
| Key Integration | Strava (added in v7.8) | Partnerships with Novartis & Johnson & Johnson |

Isomorphic Labs uses AI drug discovery models to design novel molecules and predict how candidate drugs will perform.
Visit WebsiteWhat real users say: SmartGym vs Isomorphic Labs
Not marketing copy and not our opinion — a structured sweep of public discussion (reviews, forums, communities and video comments), showing what people praise and what they complain about for each tool.
SmartGym
56 mentions across 3 sources · 100% positive (averaged across 3 sources)
Product Hunt, App Store, Bluesky
What users praise
- • Excellent Apple Watch integration with full offline independence
- • AI Smart Trainer uses periodization to auto-adjust weights and reps
- • Over 730 animated exercises with step-by-step instructions
- • 130+ professionally designed, ready-to-use workouts
What frustrates them
- • Only available on Apple devices, no Android or web
- • Mac subscription popup lacks close button in reported bug
- • Full features require a subscription after 7-day trial
- • Limited negative feedback sample may hide real issues
Researched Jul 3, 2026
Isomorphic Labs
No verifiable community signal. We scanned public discussion on Oct 14, 2026 and found posts matching the name “Isomorphic Labs”, but could not establish that they are about this product rather than something else sharing its name. Rather than publish a score built on the wrong subject, we publish none.
Who should pick which
- Apple Watch fitness enthusiastPick: SmartGym
SmartGym is the only app here, designed for Apple devices with offline watch support, 730+ exercises, and AI periodization. Perfect for tracking strength training progress.
- Big pharma VP of R&DPick: Isomorphic Labs
Isomorphic Labs partners with Novartis and J&J for large‑scale AI drug discovery. Their Drug Design Engine leverages AlphaFold for predictive protein‑ligand modeling—ideal for accelerated lead optimization.
- Athlete wanting customizable AI coachingPick: SmartGym
SmartGym’s Smart Trainer adjusts weights and reps based on actual performance. Latest update adds custom exercises and heart‑rate zones for fine‑tuned training.
- Early‑stage biotech startupPick: Isomorphic Labs
If you seek a deep‑pocketed pharma partner with foundational AI (AlphaFold), Isomorphic Labs is the only option. Their collaboration model is built for long‑term drug development programs.
Frequently Asked Questions
Can I use SmartGym on Android?
No. SmartGym is exclusive to Apple devices: iPhone, iPad, Mac, and Apple Watch.
Does Isomorphic Labs offer a public API?
No. Isomorphic Labs works only through direct pharma partnerships with Novartis and Johnson & Johnson.
What does the SmartGym subscription cost?
SmartGym Premium costs $9.99/month or $49.99/year. A free tier exists with limited features.
How much does Isomorphic Labs charge?
Pricing is not public; it is negotiated per partnership, likely involving multi‑million dollar commitments.
Does SmartGym integrate with Strava?
Yes, Strava sync was added in SmartGym v7.8 (Feb 2026).
What is the latest news about Isomorphic Labs?
Isomorphic Labs closed a Series B in February 2026, after a $600M external investment round in 2025. It also established US operations and appointed a CMO.
Can I create custom workouts in SmartGym?
Yes. You can create routines from scratch or paste text using Apple Intelligence. The latest v7.10 also adds custom exercises to the Smart Trainer.
Is SmartGym good for beginners?
Yes, it includes 730+ animated exercises with step‑by‑step instructions and automatic progression via the Smart Trainer.
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Last reviewed: July 3, 2026
