Lamin

LaminDB is an open-source data framework purpose-built to solve data management challenges in biology. It provides a unified query interface across diverse storage formats (Parquet, Zarr, AnnData, SpatialData) and databases (Postgres, SQLite), enabling researchers to trace, validate, and query millions of datasets. Designed for computational biology teams, LaminDB reduces data lineage tracking to a single line of code, supports bio-registries and ontologies, and offers LIMS/ELN capabilities. It is lineage-native, zero-lock-in, and scales from personal projects to enterprise deployments. Key features include automatic lineage capture for notebooks, scripts, pipelines, and functions; schema management and validation for biological datasets; git-like branching and merging for change management; and zero-copy data sharing across databases and storage. LaminDB integrates with Nextflow, Redun, Snakemake, Weights & Biases, MLFlow, and Vitessce, and supports local, S3, GCP, Azure, and R2 storage backends. The platform's hosted service, LaminHub, is in beta and offers free querying of public databases like the Arc Virtual Cell Atlas. Recent updates include faster Record.from_dataframe() in db 2.7.0, Excel support in sheet imports, and a database mirror for 600M-cell scRNA-seq data. LaminDB's open-source core and flexible storage options position it as a strong alternative to proprietary data management platforms for life sciences. Pricing follows a freemium model: Free (open-source core), Pro ($30/month), Team ($640+/month), and Enterprise (custom on-prem). Academic discounts are available. LaminDB best suits teams that prioritize reproducible research and need to manage heterogeneous biological data at scale.